Scientists Manage To Reverse Wrinkling And Baldness In Mice
Scientists at the University of Alabama-Birmingham have managed to reverse wrinkles and balding in mice, which could pave the way for future anti-aging products.
One of the most common and visible signs of aging is wrinkling skin and hair loss, and this could be a thing of the past if the study UAB conducted on mice can be replicated in humans. Scientists from UAB induced a mutation in the mice which caused them to wrinkle and lose hair, and when this mutation was reversed wrinkles vanished and fur regrew.
The gene that the scientists modified caused a mitochondrial dysfunction within the rodents, but were able to eliminate the effects of aging by reversing the mutation. The results of the study were published in Cell Death and Disease, and reveals that mitochondria may play a key role in hair loss and wrinkling.
The lead scientist in the study, Keshav Singh said;
“This mouse model should provide an unprecedented opportunity for the development of preventive and therapeutic drug development strategies to augment the mitochondrial functions for the treatment of aging-associated skin and hair pathology and other human diseases in which mitochondrial dysfunction plays a significant role.”
